Endoform® Antimicrobial

  • Overview
  • How it Works
  • Indications
  • Clinical Evidence
  • Product Resources
  • Ordering Information

All the benefits of a unique extracellular matrix (ECM) plus ionic silver which supports all phases of healing

• Broad spectrum antimicrobial activity for up to 7 days
• Prevents biofilm formation
• Non-cytotoxic to dermal cells



Endoform®’s unique ECM technology is designed for all phases of healing to stabilize, correct, build and organize tissue in acute and chronic wounds.

The composition of Endoform®’s ECM enables it to interact with patients’ cells during the phases of healing.

Endoform® is 85% collagen and 15% important secondary molecules including 148 structural and adhesion proteins, and glycosaminoglycans (GAGs). Endoform® only contains components that are found in tissue ECM.


Endoform® provides a biologically accurate ECM scaffold.

Endoform® is minimally processed so the ECM is not damaged. It provides a biologically accurate, porous structure that supports rapid epithelial and fibroblast infiltration. Over time the scaffold is completely remodeled as new tissue is laid down.


Endoform® helps indicate the presence or absence of proteases and restores balance.

Chronic wounds are characterized by elevated wound proteases that limit healing by digesting important dermal proteins. If Endoform® is not visible in the wound bed at the time of reapplication, this can indicate elevated wound protease activity. However, if Endoform® is visible, this can indicate that protease balance has been restored.


Endoform® Antimicrobial provides broad spectrum antimicrobial activity for up to 7 days.

Unlike some existing collagen silver dressings that have a limited duration of up to 3 days, Endoform® Antimicrobial provides sustained protection from microbial contaminants for up to 7 days, including drug resistant strains, yeasts and molds.


Endoform® Antimicrobial prevents biofilm formation.

Biofilm formation is associated with delayed wound healing and an increased risk of infection for the patient.  Endoform® Antimicrobial has been shown to prevent the formation of biofilm.


Endoform® Antimicrobial is non-toxic towards fibroblasts.

The ionic silver present in Endoform® Antimicrobial is bound to the matrix for up to seven days to provide sustained antimicrobial protection without cytotoxicity.



For product resources, click here


Product claims relating to MMP modulation and biofilm prevention are subject to local regulatory approval. Consult with your local representative for more information.

Ionic silver have been included in the Endoform® Antimicrobial to protect the device from microbial contamination. Reduction in colonization or microbial growth on the device has not been shown to correlate with a reduction in infections in patients. Clinical studies to evaluate reduction in infection have not been performed. 







Endoform® Antimicrobial Dermal Template is indicated for the management of wounds including:

  • Partial and full thickness wounds
  • Pressure ulcers
  • Venous ulcers
  • Diabetic ulcers
  • Chronic vascular ulcers
  • Tunneled/undermined wounds
  • Surgical wounds (donor sites, grafts, post Moh’s surgery, post laser surgery, podiatric, wound dehiscence)
  • Traumatic wounds (abrasions, lacerations, first and second degree burns, and skin tears)
  • Draining wounds


For product resources, click here


Instructions for Use (USA and Canada)


Brochure (USA)


Brochure (Canada)


Safety Data Sheet


For additional resources, click here.


Product claims relating to MMP modulation and biofilm prevention are subject to local regulatory approval. Consult with your local representative for more information.


For USA and Canadian customers contact your local Appulse representative or call 1-860-337-7730

For other regions contact Aroa Biosurgery